05/ 2004 Ph.D., Molecular and Cellular Biology (Cardiovascular) State University of New York
05/ 1997 M.D. Medical Degree, State University of New York
05/ 1994 M.S. Chemistry, State University of New York, Stony Brook, New York
05/ 1991 B.S. Biochemistry, State University of New York, Stony Brook, New York
08/2007-07/2008 Brigham and Women’s
Hospital, Thoracic Surgery Fellowship, Harvard Medical School, Boston,
MA
07/2004-07/2007 University
of Texas, Southwestern, Cardiothoracic Surgery Residency, Medical
Center, Dallas, TX
07/2003-06/2004 SUNY Downstate Medical Center, Chief Resident in General Surgery
07/1998-06/2003 SUNY Downstate Medical Center, Resident in General Surgery
07/1997-06/1998 SUNY Downstate Medical Center, Internship in General Surgery
09/2012-08/2013
University of Texas Medical Branch Physician Leadership Academy and
University of Houston, Inaugural Program School of Business, Clear Lake
TX Certificate of completion
2018 Hugh J. Carroll Award for Excellence in Teaching SUNY DMC
2018 New York Super Doctors list for 2018 (New York Times)
2017 Caribbean American Healthcare Awards Honoree 2017
2017 Top Doctors in Brooklyn 2017
2017 Castle Connolly Top Doctors, New York Metro Area and Brooklyn 2017
2017 New York Super Doctors list for 2017 (New York Times)
2016 Castle Connolly Top Doctors 2016
2016 Nominated to New York Super Doctors 2016 list (New York Times)
2015 Elected into the New York Surgical Society (NYSS), NYC
2015 Nominated
as a Reviewer for SUNY/Research Foundation Networks of Excellence. May
1st 2015
2015 SUNY Downstate
School of Graduate Studies Annual Research Day Judge for poster
session. April 1st 2015
2014 UTMB, General Surgery Residents Teaching Award 2014-2015
2014 Included
in “Guide to America’s Top Surgeons” by Consumers’ Research Council of
America, Washington D.C -2014 Edition
2014 “Top Doctor” peer reviewed Houstonia Magazine September 2014
2014 “Houston’s Top Doctors” in H-Texas Magazine Spring 2014
2013 Included
in “Guide to America’s Top Surgeons” by Consumers’ Research Council of
America, Washington D.C -2013 Edition
2013 “Top Doctor” peer reviewed Houstonia Magazine September 2013
2013 Included
in Texas Monthly Super Doctors “Rising Stars” July 2013 (Top 2.5% Texas
physicians).
2012 Included in
“Guide to America’s Top Surgeons” by Consumers’ Research Council of
America, Washington D.C -2012 Edition
2011 Elected
Judge- Singleton Surgical Society Resident/Fellow Research 58th
(Fifty-Eighth) Annual Scientific Program/Competition. University of
Texas, Galveston, June, 2011
2011 Included
in “Guide to America’s Top Surgeons” by Consumers’ Research Council of
America, Washington D.C -2011 Edition
2010 Included
in “Guide to America’s Top Surgeons” by Consumers’ Research Council of
America, Washington D.C -2010 Edition
2009 Mount
Sinai School of Medicine and Center of Excellence in Youth Education
and New York City Department of Education Recognition Award
2007 Included
in “Guide to America’s Top Surgeons” by Consumers’ Research Council of
America, Washington D.C -2007 Edition
2007 US Patent 7,235,588: “Method for reducing hypertension and heart failure”
President and Alumni Award for Outstanding Graduate Medical Education “Best Surgical Resident Award”, SUNY Downstate, New York
2004 Golden Apple Teaching Award, SUNY Downstate, School of Medicine, N.Y
2003 American
College of Surgeons, Trauma Paper Competition (Region II, Weill Cornell
Medical Center, New York, N.Y
2003 Elected Alpha Omega Alpha (AWA), National Medical Honor Society
2003 Recognition
Award for Innovation, Creation and Discovery. The Research Foundation
of the State University of New York, Albany, New York
2002 “Method for reducing cardiac hypertrophy and ischemia” US Patent 6,433,018
2001 Young Investigators Award, 18th Annual Eastern Hypertension Society Awards, New York
2001 Research Day Award, School of Graduate Studies, SUNY Downstate, New York
1991 Excellence Award, Outstanding Undergraduate Achievement, SUNY Stony Brook, New York
RESEARCH and SCHOLARSHIPS:
2016-present:
Institution: SUNY Downstate Medical Center/ Center for Cardiovascular and Metabolic
Diseases (NYCCMD)
Title: Molecular Analysis of Cardio-metabolic Diseases
PI: Dr. Daniel L. Beckles, MD, PhD Co-PI: Dr. Eduardo Mascareno, PhD
Funding: Herman and Olive Pascarella Professor in Cardiothoracic Surgery Research $1M
2015-present:
Institution: SUNY Downstate Medical Center
Title: Molecular Analysis of Cardio-metabolic Diseases
PI: Dr. Daniel L. Beckles, MD, PhD Co-PI: Dr. Eduardo Mascareno, PhD
Funding: SUNY DMC $50,000 initial start-up funds 02/2015 to present
Institution: SUNY Downstate Medical Center
Title: Role of F11 receptor (F11R) in neointimal hyperplasia
PI: Dr. Moro Salifu, MD, Co-PI: Dr. Daniel L. Beckles, MD, PhD
Funding: submitted for NIH funding
Institution: SUNY Downstate Medical Center
Title: Mechanisms of Myocardial Dysfunction in Aortic Valve Disease
PI: Dr. Jeffrey Borer, MD Co-PI: Dr. Daniel L. Beckles, MD, PhD
Funding: Division of Cardiology funds
Institution: SUNY Downstate Medical Center
Title:
Impact of Psychosocial Variables, Adherence and Ethnicity Outcomes
after Cardiac Surgery in an Inner-City Predominantly Black Population:
A Pilot Study
PI: Dr. Phyllis Supino Co-PI: Dr. Daniel L. Beckles, MD, PhD
Funding: American Cardiovascular Research Foundation
1999-2004
Institution: SUNY Downstate Medical Center
Title: Molecular pathways in cardiac hypertrophy
PI: Dr. M.A.Q. Siddiqui, PhD Role: Graduate Student: Dr. Daniel L. Beckles, MD
Funding: NIH grant HL53573 HL073399/ (1999 to 2004)
2001-2004
Institution: SUNY Downstate Medical Center
Titles: Role of Dehydroascorbic acid in ischemia reperfusion injury/ Molecular pathways in cardiac ischemia-reperfusion injury
PI: Dr. D.W. Golde, PhD (Memorial Sloan-Kettering Cancer Ctr., NY)
Co-PI: Dr. M.A.Q. Siddiqui, PhD
Role: Graduate Students: Dr. Daniel L. Beckles, MD/Victor H. Guaiquil
Funding: NIH grant CA30388 (2000 to 2004) NIH grant HL073399 (1999 to 2004)
MONI Genomics Enterprise Inc.:
Opened
as a privately held biomedical company dedicated to research and
development of drugs for gene-related therapy. The research operations
at MONI is an extension of projects done at SUNY Downstate Medical
Center and Center for Cardiovascular and Muscle Research, focused on
translational research and pre-clinical trial development of recently
awarded patents. President and Scientific Founder: Dr M.A.Q. Siddiqui,
PhD.
Vice President: Dr. Daniel L. Beckles, MD, PhD (2001-2004)
2000-2001
Institution: SUNY Downstate Medical Center
Title: Physiological effects of Aortic Cross-clamping in a Porcine Hemorrhagic shock model
PI: Dr. Dr. Michael E. Zenilman, MD Co-PI: Dr. Robert Schulze, MD
Research Surgery Resident: Dr. Daniel L. Beckles, MD
Funding: Department of Surgery Funds
1996-1997
SUNY Downstate Medical Center in the laboratory of Dr. Dale Distant,
M.D. Department of Transplant Surgery (4th year medical school
research). The response of radical scavengers on renal ischemia and
reperfusion injury in a rat survival model were evaluated.
Xenotransplantation was also performed in cardiac hCD59+porcine/baboon
transgenic model.
1992-1993
Moltech Corporation, Stony Brook, NY in the laboratory of Dr. Leonid
Boguslavsky, PhD (Masters of Science thesis, chapter 2). Biosensors
division: Design of polymeric biosensors for glucose detection and
complexation of organic heterocycles to heavy metals in aqueous media
as analyzed by fluorescence.
1990-1994
SUNY Stony Brook, in the laboratory of Professor Thomas W. Bell,
Department of Chemistry (Masters of Science thesis, chapter 1). 3-D
designs, macro modeling and organic synthesis of macro cyclic
artificial receptors containing chromophores and flurophores. These
artificial receptors were developed with complementary hydrogen bonding
properties to facilitate an asymmetrical host molecule and
characterized using infra red, nuclear magnetic resonance and mass
spectroscopy. I developed the first published artificial molecular
receptor to bind creatinine and exhibit a change in absorbance and
fluroscence.
PUBLISHED:
ARTICLES IN PEER-REVIEWED JOURNALS
1. Mascareno E, L. Salciccioli, K. Shreedara, D.L. Beckles. The
role of Hexim1 during pressure overload hypertrophy and cardiomyopathy
(In preparation).
2. Mascareno E, L. M. Choudhary, I Simmonds, L. Salciccioli,
D.L. Beckles. Characterization of Hexim1 as a contributing factor in
the development of Obesity induced Hypertension (In preparation).
3. Mascareno E, Geraghty P, DL Beckles. Hexim1 inhibits the
pro-inflammatory response during the development of cigarette
smoke-induced emphysema in mice (In preparation).
4. Mascareno E, D.L. Beckles, Mascareno-Dhar M. Jak2-Hexim1
signaling axis regulates prostate cancer growth (In preparation).
5. Mascareno, E., Gupta, R., Martello, L.A., Salciccioli, L., Beckles,
D.L., Walsh, M.G., Machado, F.S., Tanowitz, H.B., Haseeb, M.A.
Exacerbated Chagas disease in mice heterozygous for hexamethylene
bis—acetamide inducible–‐1 protein (Hexim-1). Microbes and Infection
2017, doi: 10.1016/j.micinf.2017.09.001
6. Dhar-Mascareno, M., Rozenberg, I., Iqbal, J., Hussain, M.M.,
Beckles, D.L., Mascareno, E. Hexim1 heterozygosity triggers remodeling
of atherosclerotic plaque and steatosis in ApoE null mice fed an
atherogenic diet. Int J Biochem Cell Bio 21;83:56-64, 2016
7. Nichols, J.E., Niles, J., Riddle, M., Vargas, G., Schilagard,
T., Ma, L., Edward, K., La Francesca, S., Sakamoto, J., Vega, S.,
Ogedegbe, M., Mlcak, R., Deyo, D., McQuitty, C., Lick, S., Beckles, D.,
Melo, E., Cortiella, J. Production and assessment of decellularized pig
and human lung scaffolds. Tissue Eng Part A 19(17-18):2045-62, 2013.
8. Lick, S.D. and Beckles, D.L. Surgical technique: partial
transplant cardiectomy mitral exposure. J Thorac Cardiovasc Surg
145(5):1413-4, 2013
9. Shah, S.K., Parto, P., Lombard, G.A., James, M.A., Beckles,
D.L., Lick, S., Valentine, V.G. Probable Phaeoacremonium parasiticum as
a cause of cavitary native lung nodules after single lung
transplantation. Transpl Infect Dis 15(1):E9-13, 2013.
10. Lick, S.D. and Beckles, D.L. A pulmonary artery “chimney” relieves RVAD anxiety. Ann Thorac Surg 94(5):1784, 2012
11. Lick, S.D. and Beckles, D.L. A simple technique to preserve
the LSVC during reoperative orthotopic heart transplant. J Cardiac Surg
27(6):767-8, 2012.
12. Takahashi, M., Beckles, D.L., Fischer, G.W., Reddy, R.C.
Epicardial sonography as a useful adjunct to repair of coronary artery
dissection. J Cardiothorac Vasc Anesth 27(2):323-325, 2012.
13. Reddy, R.C., Takahashi, M., Beckles, D.L, Farzan, F.
Anomalous right coronary artery from the left sinus – a minimally
invasive approach. European J Cardiothorac Surg 41(2):287-90; 2012.
14. Lick, S.D., Beckles, D., Piovesanna, G., Vaidya, S.,
Indrikovs, A., Barbagelata, A., Valentine, V. Transplantation of
high-PRA LVAD patients without crossmatch using on-bypass pheresis and
alemtuzumab. Ann Thorac Surg 92(4):1428-34, 2011.
15. Mascareno, E, Beckles, D.L., Dhar-Mascareno, M., Siddiqui,
M.A.Q. Enhanced hypertrophy in ob/ob mice due to an impairment in
expression of atrial natriuretic peptide. Vascul Pharmacol
51(2-3):198-204, 2009.
16. Wait, M.A, Beckles, D.L., Paul, M., Hotze, M., DiMaio, M.J.
Thoracoscopic management of empyema thoracis. J Minimal Access Surg
3(4):141-148, 2007.
17. Beckles,D.L., Mascareno, E., Siddiqui, M.A.Q. Inhibition of
Jak2 Phosphorylation attenuates pressure overload cardiac hypertrophy.
Vascul Pharmacol 45(6):350-357, 2006.
18. Mascareno, E., Beckles, D.L., Siddiqui, M.A.Q. Janus
Kinase-2 Signaling mediates Apoptosis in Rat Cardiomyocytes. Vascul
Pharmacol 43(5):327-335, 2005.
19. Blattman, S.; Deitch, J.; Beckles, D.; Gwertzman, G.;
D’Ayala, M.; McGagh, D.; Zenilmann, M.E. Infected iliac artery
pseudoaneurysm after angioplasty and stenting. Surgical Rounds Nov.
532-537, 2004.
20. Guaiquil, V.H., Golde, D.W., Beckles. D.L., Mascareno, E.,
Siddiqui, M.A.Q. Vitamin C inhibits hypoxia-induced damage and
apoptotic signaling pathways in cardiomyocytes and ischemic hearts.
Free Radical Biol Med 1;37(9):1419-29, 2004.
21. Bell, T.W.; Beckles, D.L.; Debetta, M.; Glover, B.R.; Hou,
Z.; Hung, K-Y; Khasanov, A.B. An improved preparation of
4-aminopyrimidine-5-carboxaldehyde. Organic Preparations and Procedures
International 34(3):32, 2002.
22. Beckles, D.L., Maioriello, J., Santora, V.J., Bell, T.W.
Complexation of creatinine by synthetic receptors. Tetrahedron 51(2):
363-376, 1995.
23. Boguslavsky, L., Kalash, H., Xu, Z., Beckles, D., Geng, L.,
Skotheim, T., Laurinavicius, V., Lee, H.S. Thin-film bienzyme
amperometric biosensors based on polymeric redox mediators with
electrostatic bipolar protecting layer. Analytica Chimica Acta, 311(1):
15-21, 1995
1. Siddiqui, M.A.Q., Wagner, M., Espinoza-Derout, J., Huang, F.,
Beckles, D., Mascareno, E. CLP-1-Mediated Transcriptional Control of
Hypertrophic Gene Programs Underlying Cardiac Hypertrophy (chapter 19).
In: Genes and Cardiovascular Function, Osterdal, B., Nagao, M. and
Dhalla, N., (editors) Springer: New York, New York. 2011.
2. Beckles, D.L. and Wait, M.A. The Cardiovascular System
(chapter 15). In: The Physiologic Basis of Surgery: Patrick O’Leary
(editor), Pub. Williams & Wilkins 4th Ed., 2007.
3. Bell, T.W., Beckles, D.L., Maioriello, J., Santora,
V.J., Cragg, P.J., Liu, J., Papoulis, A.T. Intrinsic Chromophores and
Fluorophores in Synthetic Molecular Receptors (chapter 7). In:
Fluorescent Chemosensors of Ion and Molecule Recognition. Czarnik, A.W.
(editor). American Chem Society Symposium Series 538 (review): pp
85-103, 1993.
4. ABSTRACTS
5. The role of Hexim1 in Chagas Disease associated
cardiomyopathy, accepted for an e-Poster presentation in the Scientific
Forum program at the American College of Surgeons. Boston Convention
& Exhibition Center, October 21-25, 2018.
6. Saving the Split: The benefits of VATS Thymectomy,
accepted for presentation in the ScientificForum program at the
American College of Surgeons Clinical Congress, October 21-25, 2018 in
Boston, MA.
7. Supino, P.G., Hai, O.Y., Avadhani, S., Nizam, R.,
Beckles, D., Borer, J.S. Low Adherence to Discharge Medications
Predicts Risk of Cardiac Events Midterm after Cardiac Surgery: A Pilot
Study among Predominantly Black Inner-City Patients. 67th Annual
Scientific Session and Expo, American College of Cardiology Florida
March 2018 (Accepted)
8. Choudhary, M., Tesfaye, , Mascerano, E., Beckles, D.
Characterization of Hexim1 as a contributing factor in the development
of hypertension. Poster Abstract at The Brooklyn & Long Island
Chapter of the American College of Surgeons, Annual Clinic Day Joint
meeting with The Nassau Surgical Society, NY. Dec 6th 2017 -1st Place
winner
9. Beckles, D.L., Bhat, A., Braverman, A.S., Gendy, A.,
Neculiseanu, E. Bacterial Pericarditis in a Young Sickle Cell Patient-a
Rare Case Report. Poster Presentation at the SCDAA 45th Annual
Convention October 25-28, 2017 Atlanta
10. Golam, SM., Mascareno, E., Beckles, DL. Characterizing the
role of Hexim1 during the progression of heart failure. Research Day
Awards Presentation , SUNY DMC April 201
11. Supino, P., Hai, O., Avadhani, S., Nizam, R., Tang, K.,
Beckles, D.L., Borer, Low Adherence to Discharge Medications Predicts
Risk of Cardiac Events Midterm after Cardiac Surgery: A Pilot Study
among Predominantly Black Inner-City Patients. American College of
Cardiology, March 2017
12. Salameh H, Khan R, Gou E, Beckles DL, Parupudi S.
Intractable Nausea and Vomiting and Weight Loss in a Young Adult: A
Rare Diagnosis to Consider. American College of Gastroenterology; Oct
22, 2014. Abstracts P672
13. Patel S, Terasaki J, Shah S, Lombard G, James M, Beckles D,
Lick S, Valentine V. Geriatric Lung Transplantation. 144(4):1016A, 2013
14. Shah SK, Patel SD, Lombard GA, James MA, Beckles DL, Lick S,
Valentine VG. Refractory and Progressive Neutrophilia after Lung
Transplantation. UTMB Annual Internal Medicine Quality and Research
Forum 2013.
15. Terasaki JM, Shah SK, Lombard GA, James MA, Beckles DL, Lick
S, Valentine VG. Airway Complication Contributing to Disseminated
Fusariosis after Lung Transplantation UTMB Annual Internal Medicine
Quality and Research Forum 2013
16. Patel SD, Shah SK, Lombard GA, James MA, Beckles DL, Lick S,
Valentine VG. Geriatric Lung Transplantation: UTMB Annual Internal
Medicine Quality and Research Forum 2013
17. Terasaki JM, Shah SK, Lombard GA, James MA, Beckles DL, Lick
S, Valentine VG. Airway Complication Contributing to Disseminated
Fusariosis after Lung Transplantation. J Heart Lung Transplant
32(4S):S267, 2013. (International Society for Heart and Lung Transplant
33nd Annual Meeting, April 2013, Montreal CA)
18. Nishi, S.P.; Shah, S.K.; Lombard, G.A.; James, M.A.;
Beckles, D.L.; Lick, S.D.; Valentine, V.G. Phaeoacremonium parasiticum
as a Cause of Cavitary Native Lung Nodules after Single Lung
Tranplantation. J Heart Lung Transplant 31(4S):S285, 2012.
(International Society for Heart and Lung Transplant 32nd Annual
Meeting, April 2012, Prague CZ)
19. Kandil, E., Zhang. H., Beckles, D., Lin, Y., Callender, G.,
Muller, C., Ocasio, V., Zenilman, M. Decreased Reg I Expression
Underlies Age-Related Impairment of Glucose Tolerance. J Surg Res.
114(2):292, 2003.
20. Mascareno, E, Beckles, D.L., Siddiqui, M.A.Q. “Jak/STAT
Signaling Mediates Myocardial Dysfunction during Hypertrophy, Ischemia
and Apoptosis”, J Mol Cell Cardiol 33(6):A10, 2003.
21. Mascareno, E, Beckles, D.L., Siddiqui, M.A.Q.” Distinct
components of the Jak/STAT Signaling Pathway dictate transcription
adaptation during myocardial hypertrophy and ischemia” Journal of
Coronary Artery Disease 4(1): 2. 2003.
22. Beckles, D.L., Mascareno, E., Siddiqui, M.A.Q. Attenuation
of cardiac hypertrophy in vivo by interference of the Jak/Stat pathway.
American Journal of Hypertension, 15(4): 166A, 2002.
23. Mascareno, E., Beckles, D.L., Das, D.K., Siddiqui, M.A.Q.
Jak/Stat signaling mediates myocardial dysfunction during hypertrophy
and ischemia. 67th Cold Spring Harbor Symposium on Quantitative
Biology, The Cardiovascular System. New York, USA. June, 2002.
24. Beckles, D.L., Chorost, M.I., Webb, H., McElhinney, J.,
Edelsberg, C., Ghosh, B. Male breast cancer in a VA population;
Abstracts of the Association of VA Surgeons, 26th Annual Scientific
Symposium. Texas, USA. April, 2002.
25. Mascareno, E., Beckles, D.L., Das, D.K., Siddiqui, M.A.Q.
Jak/Stat signaling mediates myocardial dysfunction during hypertrophy
and ischemia. Keystone Symposia, Jak and STATs: Activation and Biologic
Impact. Colorado, USA. Jan., 2002.
26. Mascareno, E, Beckles, D.L., Siddiqui, M.A.Q. Leptin: a
novel regulator of pressure-overload hypertrophy. Circulation 106(19):
1541, 2002.
27. Beckles, D.L.; Mascareno, E.; Siddiqui, M.A.Q. Inhibition of
the Jak/STAT pathway with a specific Jak2 inhibitor (AG490) attenuates
hypertrophy in an in vivo murine model. J Mol Cell Cardiol 33(6):A10,
Jun., 2001.
28. Mascareno, E., Beckles, D.L., Das, D.K., Siddiqui, M.A.Q.
Activation of Jak/STAT signaling mediates myocardial dysfunction during
pressure overload hypertrophy and ischemia/ reperfusion. Journal of
Coronary Artery Disease 4(1): 2, 2001.
29. Boguslavsky, L., Kalash, H., Xu, Z., Beckles, D.L., Geng,
L., Skotheim, T., Laurinavicius, V., Lee, H.S. Thin-film Bienzyme
Amperometric Biosensors Based on Polymeric Redox Mediators. Biosensors
and Bioelectronics, 11(1/2): xvii, 1996.
30. Beckles, D.L., Maioriello, J., Santora, V.J., Bell, T.W.,
Chapoteau, E., Czeck, B.P., Kumar, A.,Response of intrinsic
chromophores and fluorophores to complexation of creatinine; American
Chemical Society 206: 256- ORGN, Pt 2 Aug 22, 1993.
31. Lee, H.S., Lan, H.L., Beckles, D.L., Boguslavsky, L., Gene,
L., Okamoto, Y., Skotheim, T.A. Amperometric hydrogen-peroxide sensors
based on quinone-containing polymers; American Chemical Society 205:
33-IEC, pt 1 Mar 28, 1993
1. Annual Research Day, School of Graduate Studies, “The role of Hexim1
in Chagas Disease associated cardiomyopathy’ State University of New
York, Downstate Med. Ctr., N.Y., 2018
2. Annual Research Day, School of Graduate Studies, “Left
Ventricular Assist Devices – Past, Present, and Future” State
University of New York, Downstate Med. Ctr., N.Y., 2018
3. Bacterial Pericarditis in a Young Sickle Cell Patient-a
Rare Case Report Poster Presentationat the SCDAA 45th Annual Convention
October 25-28, 2017 Atlanta
4. Thirty-seventh (37th) Annual Meeting, Association for
Academic Surgery. “Down-regulated Reg I Expression Underlies
Age-Related Impairment of Glucose Tolerance”. Sacramento, California.
Nov., 2003.
5. Committee on Trauma, American College of Surgeons, Div
II “Emergent Thoracic Aorta Cross-clamping Offers No Additional
Benefits Over Fluid Resuscitation in a Hemorrhagic Porcine Model”.
Weill Cornell Medical Center, NY, 2003 (Moderators: Dr. Palmer Q.
Bessey and Dr. Gregory J. Jurkovich).
6. Eighteenth (18th) Annual Eastern Hypertension Society,
“Attenuation of Cardiac Hypertrophy in vivo by Interference of the
Jak/Stat Pathway”. New York, NY, 2002 (Moderator: Dr. Lawrence R.
Krakoff, Mt Sinai Medical Ctr. NY).
7. Sixty-seventh (67th) Cold Spring Harbor Symposium on
Quantitative Biology, The Cardiovascular System. “Jak/Stat signaling
mediates myocardial dysfunction during hypertrophy and ischemia” New
York, June, 2002
8. Keystone Symposia, Section: Jak and STATs: Activation
and Biologic Impact. “Jak/Stat signaling mediates Myocardial
dysfunction during hypertrophy and ischemia” Colorado, USA. Jan., 2002.
9. Eighty-eighth Indian Science Congress, Section of
Biochemistry, Biophysics and Molecular Biology. “The Role of Jak/STAT
Signaling Pathway in Myocardial Hypertrophy and Ischemia”. New Delhi,
India Jan., 2001
10. Fifth Annual Research Day, School of Graduate Studies, “The
Jak/Stat Pathway in Cardiac Hypertrophy”, State University of New York,
Downstate Med. Ctr., N.Y., 2001
11. XVII World Congress of the International Society for Heart
Research, “Inhibition of the Jak/STAT pathway with a specific Jak2
inhibitor (AG490) attenuates hypertrophy in an in vivo murine model”
Winnipeg, Canada, Jun., 2001.
12. Eightieth (80th) Annual Meeting of the American Chemical
Society, “Response of intrinsic chromophores and fluorophores to
complexation of creatinine”, Chicago, Aug., 1993
13. Third (3rd) Annual Undergraduate Research Educational and
Creative Activities (URECA) symposium; “Complexation of Creatinine by
an Artificial Receptor”, State University of New York, Stony Brook,
N.Y., 1991.
- Doctor of Philosophy (PhD)
Dissertation by Beckles, D.L.; State University of New York, Downstate
Medical Center. Title: The Role of Jak2 Kinase Signaling in the
Induction of Cardiac Hypertrophy and Apoptosis, 2004.
- Master of Science(M.Sc.)
Thesis by Beckles, D.L. State University of New York at Stony Brook.
Title: Design and Synthesis of Artificial Receptors containing
Chromophores and Flurophores, 88 leaves, 1994.
Intellectual Property and Patents
2002 “Method for reducing cardiac hypertrophy and ischemia” US Patent 6,433,018
2007 “Method for reducing hypertension and heart failure” US Patent 7,235,588
TEACHING RESPONSIBILITIES AT SUNY Downstate Medical Center:
Department of Surgery, Division of Cardiothoracic Surgery:
2/2015
to present: Bedside teaching of medical students, residents and
fellows; lectures to medical students, PA students, nurses and surgical
residents; supervision of general surgery residents in performing
surgical procedures, perioperative and postoperative care of cardiac
and thoracic surgery.
School of Medicine:
2016 to present: MS1 Anatomy-Embryology: Cardiovascular and Respiratory UNIT5 lecturer
MS3 and MS4 General Surgery Clerkship Lecture Series- Cardiothoracic Surgery
School of Allied Health Professionals:
2016 to present: Physician Assistant student lecture cardiothoracic Surgery
Department of Medicine, Division of pulmonary and critical care medicine:
2016 to present: Pulmonary Fellow conference
Department of Medicine, Division of Cardiology:
2015 to present: Teaching weekly cardiac cath conferences (Heart Team)
Teaching weekly Journal Club
TEACHING RESPONSIBILITIES AT University of Texas Medical Branch:
Department of Surgery, Division if Cardiothoracic Surgery:
06/2010-01/2015: Bedside teaching of medical students, residents, and
fellows; lectures to medical students, nurses, and surgical residents;
supervision of general surgery residents in performing surgical
procedures, perioperative and postoperative care of cardiac and
thoracic surgery.
UTMB (SOM) Gastrointestinal/Nutritional Facilitator 2011-2012
Division of Pulmonary and Critical Care Medicine Clinical Conference:
06/2010-01/2015: Annual Fellow Conference: Surgical management of chest diseases
Division of Hematology Oncology:
06/2010-01/2015: Annual Fellow Conference: Surgical Treatment of Thoracic Malignancies